Includes bibliographical references and index.

Advances in capsule formulation and filling / Larry L. Augsburger and Stephen W. Hoag -- An introduction to two-piece hard capsules and their marketing benefits / Dennis Murachanian -- Hard shell capsules in clinical trials / Moji Christianah Adeyeye and Amusa Adebayo -- Manufacture of capsule shells / Brian E. Jones, Fridrun Podczeck and Paul Lukas -- Non-gelatin based capsules / Sven Stegemann -- Hard shell capsule filling machines / Donald K. Lightfoot -- Instrumented capsule filling machines and filling machine simulators / Vikas Moolchandani and Larry L. Augsburger -- Dry-fill formulation and filling technology / Pavan Heda, Vikas Agarwal and Shailesh K. Singh -- Plug formation / Fridrun Podczeck and Brian E. Jones -- Modeling powder filling during encapsulation / Ammar Khawam -- Scaling-up and transfer of hard shell formulations across machine types / Larry L. Augsburger and Michael Levin -- Modified release delivery systems : extended release capsule platform / Reza Fassihi -- Analytical testing and evaluation of capsules / Stuart L. Cantor and Asis K. Dutta -- Rheological aspects of capsule shell excipients and the manufacture of encapsulated formulations / Lawrence H. Block -- Quality-by-design (QBD) for capsule formulation and process development : regulatory science developments, scientific case studies, and future challenges / Huiquan Wu, Lin Xie, Stephen W. Hoag, Larry L. Augsburger, Mansoor Khan.